This is in UroToday, 08 March 2005:
"BERKELEY, CA (UroToday Inc.) - Dr. Sergio Nicolau and colleagues from Sao Paulo, Brazil performed a study to determine the prevalence of human papilloma virus (HPV) in the male partners of HPV-infected women, as well as define the most affected site in genitalia and compare diagnostic methods for the detection of HPV infection in men. Their findings were published in the February 2005 edition of Urology.
They studied 50 male, stable, sexual partners of women confirmed to be HPV-infected. Subjects underwent two examinations. At the first visit, the subjects completed a standardized questionnaire, and had specimen brushings taken from six different areas in the anogenital region: glans, preupuce internal surface, distal urethra, prepuce external surface, scrotum, and anus. These brushing were tested for HPV DNA using the standard hc2 method. One week later the same subjects underwent peniscopy with acetic acid testing and all clinical and subclinical lesions were biopsied. The biopsied specimens were divided in two and underwent both histopathologic examination for the presence of koilocytotic cells, indicative of HPV infection, and HPV hc2 testing.
The authors concluded that HPV DNA testing is the best method to diagnose HPV infection. The use of the hc2 test on brushed specimens was more sensitive than the more traditional method of peniscopy, biopsy, and histopathologic examination. They recommend obtaining brushed material from the prepuce and distal urethra with HPV DNA testing as the optimal method for diagnosing HPV infection."