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National Cervical Cancer Coalition


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 Post subject: 24/7 symptoms
PostPosted: Fri Mar 26, 2010 12:27 am 

Joined: Fri Mar 19, 2010 12:17 am
Posts: 8
Location: San Francisco
For 3/4 weeks I had what felt like a mild yeast infection or sometimes razor rash which I mentioned to my ob/gyn at my annual visit. He found a small sore which was cultured and came back negative for herpes. As the symptoms continued, I had a blood test (don't know which type or the actual results) but was told it was positive for both oral and genital herpes. That was February 18 and I've been taking 400mg of acyclovir daily since but nothing has changed! This has been going on since December and I can't find anything anywhere that describes these constant symptoms. Most of the time I'm not aware of them unless I think about it, but they've never really gone. Boyfriend at the time says he's negative, but I feel like my life is on hold until I figure out what's going on. Am I continually active or constantly on the verge of having an active outbreak? Any thoughts or suggestions on what do do next would really help.


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 Post subject: Re: 24/7 symptoms
PostPosted: Fri Mar 26, 2010 3:47 am 

Joined: Mon Feb 05, 2007 11:47 am
Posts: 5443
Location: PA
Acyclovir needs to be taken 2x/day for suppressive therapy. when you have active symptoms, increase it to either 800mg 3x/day for 2 days or 400mg 3x/day for 5 days to help speed healing.

I also recommend going back to be seen again and get retested for yeast and bacterial infections genitally too.

betsy

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 Post subject: Re: 24/7 symptoms
PostPosted: Mon Mar 29, 2010 1:51 am 

Joined: Fri Mar 19, 2010 12:17 am
Posts: 8
Location: San Francisco
Thanks Betsy. I'll make an appointment and will also find out what type of test I had and the results.


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 Post subject: Re: 24/7 symptoms
PostPosted: Fri Apr 02, 2010 10:49 pm 

Joined: Fri Mar 19, 2010 12:17 am
Posts: 8
Location: San Francisco
Went back to my doctor but saw the NP this time who was very helpful. No yeast or bacteria and thought symptoms were herpes related but agreed acyclovir dose was too low and I now have a prescription for Valtrex, 1g daily. My blood test, taken about six weeks after last exposure, was Herpes Select and showed 1.5 IgG for oral and 2.5 IgG for genital herpes. I asked for another test and I have the paperwork but was told it really wouldn't make a difference - I have herpes, period! That seems to make sense, but I'd really appreciate hearing what you have to say. Thanks.


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 Post subject: Re: 24/7 symptoms
PostPosted: Sat Apr 03, 2010 12:01 am 

Joined: Mon Feb 05, 2007 11:47 am
Posts: 5443
Location: PA
Actually your hsv2 is a low positive and needs confirmed with further testing. Since you don't have a lesion culture that is hsv2+, this is in your best interest to have done. Herpes will not give you non-stop symptoms for 3+ months.

A herpes WB is your best bet. Being from california, this should be easily attained for you from your provider.

betsy

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 Post subject: Re: 24/7 symptoms
PostPosted: Sat Apr 03, 2010 8:20 pm 

Joined: Fri Mar 19, 2010 12:17 am
Posts: 8
Location: San Francisco
Hi Betsy,

Just looked at my paperwork for the blood test and it asks for HerpeSelect again, but I can certainly call my doctor and ask for a new order for Western Blot. However, I'm totally baffled. What would the Western Blot test show that HerpeSelect wouldn't? Isn't positive positive no matter how low? Thanks for your help with all this. I keep thinking I've got a handle on this, but there always seems to be more that I need to know. This board is a great help.


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 Post subject: Re: 24/7 symptoms
PostPosted: Sat Apr 03, 2010 10:27 pm 

Joined: Mon Feb 05, 2007 11:47 am
Posts: 5443
Location: PA
the WB looks at more of the igg response to herpes than the herpeselect does. It's often helpful in ruling out false positives.

betsy

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 Post subject: Re: 24/7 symptoms
PostPosted: Sun Apr 04, 2010 9:56 pm 

Joined: Fri Mar 19, 2010 12:17 am
Posts: 8
Location: San Francisco
Hi Betsy,

With a low positive, does a second herpeselect test taken two months later often give different results? Thanks again.


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 Post subject: Re: 24/7 symptoms
PostPosted: Mon Apr 05, 2010 10:33 am 

Joined: Mon Feb 05, 2007 11:47 am
Posts: 5443
Location: PA
if it was a newly acquired infection when you were first tested, repeating the test again sometimes gives you a result over the false positive cut off which helps you confirm your status. If it was a false positive, sometimes repeating the test later gives you a clear negative so that you confirm that your first test was a false positive. Sometimes it returns with a low positive again which leads to the WB to confirm your status.

I can help you with your new results when you get them if you need it :)

betsy

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 Post subject: Re: 24/7 symptoms
PostPosted: Mon Apr 05, 2010 7:39 pm 

Joined: Fri Mar 19, 2010 12:17 am
Posts: 8
Location: San Francisco
Thanks again. I'm sure I'll be in touch once I have the second test results.


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 Post subject: Re: 24/7 symptoms
PostPosted: Wed Apr 21, 2010 12:11 am 

Joined: Mon Feb 08, 2010 11:13 pm
Posts: 7
Location: san jose
Hi There,

I was diagnosed with HSV2 in January and seem to have the same problem with 24/7 symptoms. Everytime I think the herpes has gone away, I get another breakout. My NP told me to take 400mg of Acyclovir once a day for suppression therapy, and the herpes still came back once I started my period. After going through 5 days of 400mg Acyclovir 3 times a day, I am now trying 800mg Acyclovir once a day, but the lesions are still present. Is it possible I have built up a resistance to the antiviral? Is there anything else I can do to manage the OB's?? Thank you for your help!


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 Post subject: Re: 24/7 symptoms
PostPosted: Wed Apr 21, 2010 9:38 am 

Joined: Mon Feb 05, 2007 11:47 am
Posts: 5443
Location: PA
mkm...did you ever do the follow up testing for yeast and bacterial infections like I recommended in your prior post?

acyclovir is not effective when only taken once a day. it needs to be 400mg 2x/day in order to be effective.

the vast majority of the time when folks are having non-stop symptoms, it's not their herpes that is causing them all the time. definitely pursue a further work up.

betsy

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 Post subject: Re: 24/7 symptoms
PostPosted: Wed Apr 21, 2010 9:15 pm 

Joined: Mon Feb 08, 2010 11:13 pm
Posts: 7
Location: san jose
Hi Betsy,

Yes, I had a PAP smear about a month ago and I even called my NP today to make sure there were no bacterial or yeast infections. I also switched my dose of Acyclovir to 400mg twice a day by breaking up my 800mg pill.... why do they only sell them in 800mg if they are supposed to be taken as 400mg?? Any other ideas for why the herpes keeps coming back? Could it be the hormones from my period? Thanks for your help!


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 Post subject: Re: 24/7 symptoms
PostPosted: Thu Apr 22, 2010 6:12 am 

Joined: Mon Feb 05, 2007 11:47 am
Posts: 5443
Location: PA
there was an acyclovir shortage for awhile which could be why you got 800mg tablets. otherwise it's the way your provider wrote the prescription for you. they come in 200mg and 400mg tablets too.

I'd go back when you have symptoms again for a work up again. I know it's a pain but it's time to get to the bottom of this all. if symptoms are typically with your period, it could be any number of things going on.

betsy

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 Post subject: Re: 24/7 symptoms
PostPosted: Mon Apr 26, 2010 11:04 pm 

Joined: Mon Feb 08, 2010 11:13 pm
Posts: 7
Location: san jose
So my symptoms came back again today, and I am supposed to start my period any day now.... Now I am almost positive that the two are related! I am in Idaho for an internship and have never used my Aetna health insurance outside of my school's health center. Should I go see a OBGYN or a STD specialist (if that exisits?) or go to the local planned parenthood. I am not sure what else they can do for me? I am on antivirals... is there another treatment that I don't know about? I don't want to go see someone if they are just going to tell me what I already know, but it is really frustrating that I can not get rid of the herpes.


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